The epigenetic test built for men

Find out how old yourbody actually is.

One saliva sample reads your DNA and your epigenetics. Your AlphaAge and your pace of ageing, ten reports with clear actions, and an AI coach that reads only your results.

Scientific. Personal. Actionable.
18:55 95%
ST
DashboardPower Your Biology
Hey there, I’m EngneAI!
Ask me anything...
DNA ResultsSome of your DNA results
Metabolic Rate

Your metabolic rate is within the normal range, indicating an average calorie burn.

Genetic Bone Mineral Density

Your genetic bone mineral density is normal, with no current concerns.

GI Health

Your gut response markers show a stable baseline.

Epigenetic ResultsSome of your Epigenetic results
Biological Age
32
4.6 years younger
Recovery Score
74 /100
Optimal
Pace of Ageing
0.89×
Slower than average
DNA Markers
285
CpG sites

SCIENCE LEd  |  DATA DRIVEN  |  BUILT FOR MEN

The Problem

Your results came back normal. So why don’t you feel it? Because you’re not the average of a man and a woman, and half the signal calling you normal was never yours. Men age on a different clock, with different methylation, different hormones and a different pace entirely.

Hormone signalling reduced
Cellular maintenance slowing
Oxygen ceiling below average
Inflammation trajectory rising
One average setting. Blind to every actual man.

AlphaAge was trained on male data only, so the number it gives you is about you and nobody else.

01The first epigenetic clock built on purely male data
0.88
R² on men

285 CpG sites

On women it drops to 0.77

A blood test reads the moment. ENGNE reads the direction.

A BLOOD TEST  ·  THE MOMENT
BIOLOGICAL AGE (SINGLE SNAPSHOT)
Markers
Result: 34.0
Ref. Range: N/AStatus: Fixed
Static Data Panel

What’s happening today

A blood test measures what’s in you right now. It’s the right tool for catching what’s acutely wrong, and it’s the one your GP will run. What it doesn’t show is how fast you’re ageing.

SALIVA  ·  THE DIRECTION
Trend Vector:  -2.1 units/yr|Retest Frequency:  Tri-annual
BIOLOGICAL AGE
Retest 1Retest 2Retest 3Retest 4Retest 5TODAYFUTURE DIRECTION
TIME

Which way you’re going

ENGNE reads the layer underneath. Retest and you get a line rather than a dot, so you can see which way you’re heading and what changed it.

Follow the protocol, retest, and watch what moves.

ENGNE spit tube

Order & Test

Two minutes of saliva at your kitchen table. No needles, no clinic, no fasting. Post it back in the prepaid pack.

01

See Your Results

Over 1,500 biomarkers analysed in a CLIA certified lab. Your reports land in the app in four to six weeks, with a protocol built around your data.

02
ENGNE results phone
ENGNE DNA box

Follow & Retest

Act on your data. Retest every quarter or six months and watch how your body responds.

03

WHAT YOU GET

Your DNA shows what could be. Your epigenetics show what may be moving. Every report reads both, so you see what you were born with and how those genes are expressing now. Your DNA half stays the same for life. Your epigenetic half is the part that changes.

07 Epigenetic results
AlphaAge Body age Heart age EpiVitality Immunoscore MethylGuard Prostate health
01

Cardiac Health

02

Gut Health

03

Harley Hair

04

Libido

05

Muscle Building

06

Nutrition

07

Stress and Sleep

08

Testosterone Optimisation

09

Weight Loss

10

Longevity

After your test you get your AlphaAge, your true male biological age.

0.89× pace
32
Your biological age
4.6 years younger
Recovery top driver this cycle
Month 6 next retest
37 32

EngneAI reads your own DNA, your epigenetics, your goals and your progress, then answers in plain language, from whether your MTHFR variant means you should take methylation support to how hard you should train this week. It sharpens every time you retest, and the model behind it gets stronger every time someone new joins.

PERSONAL BIOLOGY INTERFACE
18:56
95%

Hey there, I'm
EngneAI!

Ask about your body...

Not sure where to begin?Start with one of these:

ENGNE app bottom navigation

Every clock before AlphaAge averaged male biology into mixed data. AlphaAge was rebuilt around men from the first signal.

01
Male biology standard AlphaAge
Validated signal The only clock built purely on male data.
0.88 R² on men
Male-trained biology Yes
Epigenetic age Yes
Age read from DNA Yes
Androgen-linked loci Yes
Pace of ageing Yes
Pan-tissue clocksMixed-sex clock
No Yes Yes Mixed No
Pace-of-ageing clocksRate model
No Rate only No Mixed Yes
Wearable biological ageBehavioural estimate
No No No No No
Single-cohort mixed-sex clocksMixed-sex cohort model
No Yes Yes Yes No
AlphaAge is not a refinement. It is a male-first rebuild. Signal comparison / 04

Before your data says anything specific, every man needs the same handful of things. These five are included with every plan. Your reports decide the doses. Your next retest decides what changes.

The five foundationsDaily baseline
01 Heart + brain
OMEGA-3 HEART + BRAIN 60 CAPSULES
Foundation 01

Omega-3

Cardiovascular signal

EPA / DHA60 capsules
02 Hormones + immunity
VITAMIN D3 HORMONES + IMMUNITY 60 CAPSULES
Foundation 02

Vitamin D3

Male hormone support

D3 / 4000 IU60 capsules
04 Thyroid + defence
SELENIUM+ THYROID + DEFENCE 60 CAPSULES
Foundation 04

Selenium+

Cellular protection

SE / ZN60 capsules
05 Energy + focus
B-COMPLEX ENERGY + FOCUS 60 CAPSULES
Foundation 05

B-Complex

Methylation support

B6 / B9 / B1260 capsules
Launching with every plan

Start everyone in the same place. Let the data separate them.

Monthly from launch

The test tells you where you are. Only a retest tells you whether anything you changed worked.

Choose your feedback loop Same science. Different retest cadence.
One connected system DNA, epigenetics and app intelligence
Keep the app for life Your data remains yours
Three-month minimum on monthly plans Then cancel any time from the app

Four world-level fighters, testing exactly the way you would.

Male-first performance intelligence Four champions, tested.
Jonathan Haggerty, ONE Kickboxing World Champion
ENGNE / 01 Champion profile
01

Jonathan Haggerty

ONE Kickboxing World Champion

Tested withENGNE

George Jarvis, WBC Muay Thai World Champion
ENGNE / 02 Champion profile
02

George Jarvis

WBC Muay Thai World Champion

Tested withENGNE

Sam Noakes, British and European Champion
ENGNE / 03 Champion profile
03

Sam Noakes

British & European Champion

Tested withENGNE

Nathaniel Wood, UFC Top 10
ENGNE / 04 Champion profile
04

Nathaniel Wood

UFC Top 10

Tested withENGNE

01 / 04
Powered by DEPH Labs

A physician-scientist with a PhD from King's College London, a published epigenetic-clock author, and the platform team behind DEPH Labs.

Dr Saima Ajaz
The science & IP engine

Dr Saima Ajaz

CEO · DEPH Labs

A physician-scientist at the frontier of metabolic and longevity medicine. Harvard-certified in lifestyle and nutritional medicine and a Diplomate of the American Board of Regenerative Medicine, she holds a PhD from King's College London, where she is Honorary Senior Clinical Lecturer. Across 20+ years at the Institute of Liver Studies, King's College Hospital, her research into mitochondrial bioenergetics and non-invasive biomarkers produced the patented biomarker panels at the core of DEPH's IP. She is Medical Director of the Harley Street Longevity Club and co-founder of UmmuHub.

Visit DEPH Labs
Clinical science layer Biomarker architecture
Lisa Loud
Consumer platform & ownership layer

Lisa Loud

CEO · DEPH Network

A proven operator who has scaled technology from inside the giants to the frontier of crypto. After Apple and PayPal, she went on to build and lead several multibillion-dollar blockchain protocols and networks, as CMO of BitMEX, COO of ShapeShift and a senior leader at Secret Network. Named to Forbes' Top 100, she now leads DEPH Network: the consumer platform and blockchain ownership layer that turns the science into something people own, control and are rewarded for.

Visit DEPH Network
Platform layer Consumer execution
Christopher Collins
01

Christopher Collins

Chief Epigenetics Officer

Architect of the sex-specific clocks and a published epigenetic-clock author, including a peer-reviewed saliva clock (DNA, 2025).

Clock development Epigenetics
Aaron Hudson
02

Aaron Hudson

Chief Technology Officer

Leads engineering across the apps, data platform and infrastructure.

Engineering systems Infrastructure
Sam Thompson
03

Sam Thompson

Founder · Commercial Director

Integrates legal, brand, product, science and commercial into one engine.

Commercial integration Founder
Melody Maker
04

Melody Maker

CMO · Creative Director

Owns the brand, the story and the creative direction across DEPH.

Brand system Creative
Luke James
05

Luke James

Sales Director

Drives commercial growth, partnerships and clinical channel sales.

Clinical channels Sales
Dr Kennedy Obiekwe
06

Dr Kennedy Obiekwe

Head of Sports Medicine

Translates the science into performance, recovery and longevity protocols.

Sports medicine Performance
Dr Mahd Siddiqi
07

Dr Mahd Siddiqi

Clinical Medicine · MedTech

Bridges frontline clinical practice with product and diagnostics.

Clinical delivery MedTech
Your data

Encrypted at rest. Never sold. Never shared unless you say so, and the default is no.

Nothing moves without your permission.
Partnerships & press

01
Partnership Network / Longevity
Launch partner

Harley Longevity Club

ENGNE / 01 Longevity
02
Partnership Network / MMA
Performance partner

GB Top Team

ENGNE / 02 MMA
03
Partnership Network / Fighters
Athlete network

Sports Performance Solutions

ENGNE / 03 Performance
ENGNE / PARTNER NETWORK / 03 Performance. Longevity. Athlete network.
Before you start

Everything worth knowing before your first sample.

ENGNE preparation protocol 06 questions / testing / reports / AlphaAge / plans
Question index 06 entries
  1. Still get bloods. They catch what’s acutely wrong today, and nothing here replaces that. What a blood draw can’t tell you is how fast you’re ageing. ENGNE reads your epigenetics and tracks that over time.

  2. Over 1,500 biomarkers from one sample. Ten reports that read your DNA and your epigenetics together, and seven epigenetic results led by AlphaAge. EngneAI turns all of it into a plan.

  3. Most health AI gives general advice. EngneAI uses your own DNA, epigenetic results, goals and progress, so it can answer things like whether your MTHFR variant means you should take methylation support.

  4. Validated on an independent male cohort by our research team. On women it drops to 0.77.

  5. No needles. A simple saliva swab at home, posted back prepaid. Reports in around four to six weeks.

  6. Yes, any time after your 3-month minimum, straight from the app.

285 CpG sites

Male-Trained Data

Published Saliva Clock

Retest And Compare

ENGNE provides wellness, performance and longevity insights, not medical advice. It is not a medical device and does not diagnose, treat or screen for any disease or condition. Biological age results are estimates.

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